The effects of microsurgical varicocelectomy performed for infertility on premature ejaculation

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dc.authorscopusidAbdulmecit Yavuz / 57197735378
dc.authorwosidAbdulmecit Yavuz / JGE-0259-2023
dc.contributor.authorKızılkan, Yalçın
dc.contributor.authorDuran, Mesut Berkan
dc.contributor.authorKayra, Mehmet Vehbi
dc.contributor.authorŞahin, Bahadır
dc.contributor.authorYavuz, Abdulmecit
dc.date.accessioned2025-05-08T10:43:28Z
dc.date.available2025-05-08T10:43:28Z
dc.date.issued2024
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, İSÜ Hastaneleri
dc.description.abstractPurpose To investigate the effects of varicocelectomy on premature ejaculation (PE) in patients with varicocele and infertility. Methods A total of 82 sexually active patients aged 18 years or over who had undergone microscopic subinguinal varicocelectomy with a clinical diagnosis of varicocele in 14 urology clinics between October 2021 and March 2023 with primary infertility were evaluated prospectively Patients were evaluated using the Turkish validated form of the 'Premature Ejaculation Diagnostic Tool' (PEDT) scale. A PEDT score of 11 or above was taken to indicate the presence of PE. Turkish validated forms of PEDT and International Index of Erectile Function-5 (IIEF-5) were completed in all patients pre-operatively and at 3 and 6 months post-operatively. Intravaginal ejaculatory latency time (IELT) and serum testosterone measurements were also recorded. Results Left varicocelectomy was performed in 70.7% and bilateral varicocelectomy in 29.3% of the participants. A significant difference was found between pre- and post-operative PEDT scores (x 2 (2) = 130.1, p < 0.001). A significant difference was observed between pre- and post-operative IELT time (x 2 (2) = 143.2, p < 0.001). IIEF-5 scores differed before and after surgery (x 2 (2) = 59.5, p < 0.001). A difference was found between the testosterone levels measured before and after surgery (x 2 (2) = 40.9, p < 0.001). No statistically significant difference was observed between the third- and sixth-month testosterone values (p = 0.183). Testosterone levels (p = 0.001) and IELT scores (p < 0.001) were significantly higher, while PEDT scores (p < 0.001) were significantly lower in the bilateral varicocelectomy group at the sixth post-operative month. Conclusion In light of our findings, it is recommended that infertile patients with varicocele be informed of the positive effects of varicocelectomy on PE.
dc.identifier.citationKizilkan, Y., Duran, M. B., Kayra, M. V., Sahin, B., Toksoz, S., Gultekin, M. H., ... & Turunc, T. (2024). The effects of microsurgical varicocelectomy performed for infertility on premature ejaculation. International Urology and Nephrology, 1-7.
dc.identifier.doi10.1007/s11255-024-04330-z
dc.identifier.endpage1431
dc.identifier.issn0301-1623
dc.identifier.issn1573-2584
dc.identifier.pmid39708194
dc.identifier.scopus2-s2.0-85212811700
dc.identifier.scopusqualityQ2
dc.identifier.startpage1425
dc.identifier.urihttp://dx.doi.org/10.1007/s11255-024-04330-z
dc.identifier.urihttps://hdl.handle.net/20.500.12713/7236
dc.identifier.wosWOS:001382504800001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorYavuz, Abdulmecit
dc.institutionauthoridAbdulmecit Yavuz / 0000-0001-6141-3931
dc.language.isoen
dc.publisherSpringer science and business media b.v.
dc.relation.ispartofInternational urology and nephrology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectErection
dc.subjectInfertility
dc.subjectPremature Ejaculation
dc.subjectVaricocelectomy
dc.titleThe effects of microsurgical varicocelectomy performed for infertility on premature ejaculation
dc.typeArticle

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