Secondary pituitary abscess: a rare complication of transsphenoidal surgery for pituitary adenoma - description of two new cases and review of the literature

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dc.authorscopusidOzan Başkurt / 57209880021
dc.authorscopusidNurperi Gazioğlu / 6601973313
dc.authorwosidOzan Başkurt / AAH-3664-2020
dc.authorwosidNurperi Gazioğlu / AAJ-3648-2021
dc.contributor.authorBaşkurt, Ozan
dc.contributor.authorAvinçsal, Benan Baysoy
dc.contributor.authorDiren, Furkan
dc.contributor.authorKabataş, Serdar
dc.contributor.authorKuşoglu, Hülya
dc.contributor.authorKara, Simay
dc.contributor.authorGazioğlu, Nurperi
dc.date.accessioned2025-04-18T09:48:57Z
dc.date.available2025-04-18T09:48:57Z
dc.date.issued2024
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü
dc.description.abstractBackground: Pituitary abscess (PA), a rare complication following transsphenoidal (TS) surgery for pituitary adenoma with an incidence of 0.2%, poses a significant risk; carrying potential morbidity, recurrence, and the necessity for reoperation. Timely suspicion, diagnosis, and treatment are imperative.Patients and Methods: We present two cases and provide a literature review on the symptoms, risk factors, diagnosis, treatment, and outcomes associated with secondary PAs following TS surgery for adenoma.Results: We identified 12 articles reporting a total of 45 cases, in addition to our 2 cases. The primary symptoms were headache and visual impairment, with no fever or specific infectious parameters observed. Predominant risk factors identified included cerebrospinal fluid (CSF) leakage and prior radiotherapy (RT). Our first patient, a 45-year-old male, presented 10 weeks after TS surgery with sudden-onset symptoms, whereas our second patient, a 64-year-old female, presented 22 years postoperatively. In the first case, intraoperative CSF leakage, with the patient's history of allergic rhinitis and frequent nasal irrigation possibly contributed to the development of abscess. In the second case, RT was considered a potential risk factor. Severe headache and subclinical signs of infection associated with a cystic lesion of the pituitary gland were common findings. Both patients underwent endoscopic TS drainage and received appropriate antibiotic therapy, resulting in complete recovery without recurrence.Conclusions: When faced with severe headaches in a patient with a history of TS surgery for a pituitary adenoma, coupled with radiological evidence showing a cystic appearance with peripheral enhancement, taking a proactive approach to promptly identify and intervene in secondary PAs is essential for mitigating potential complications and optimizing patient outcomes.
dc.identifier.citationBaskurt, O., Baysoy Avinçsal, B., Diren, F., Kabatas, S., Kusoglu, H., Kara, S., & Gazioglu, N. (2024). Secondary Pituitary Abscess: A Rare Complication of Transsphenoidal Surgery for Pituitary Adenoma-Description of Two New Cases and Review of the Literature. Surgical Infections, 25(8), 612-623.
dc.identifier.doi10.1089/sur.2024.077
dc.identifier.endpage623
dc.identifier.issn1096-2964
dc.identifier.issn1557-8674
dc.identifier.issue8
dc.identifier.pmid39058677
dc.identifier.scopus2-s2.0-85199990532
dc.identifier.scopusqualityQ2
dc.identifier.startpage612
dc.identifier.urihttp://dx.doi.org/10.1089/sur.2024.077
dc.identifier.urihttps://hdl.handle.net/20.500.12713/6870
dc.identifier.volume25
dc.identifier.wosWOS:001276434700001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorBaşkurt, Ozan
dc.institutionauthorGazioğlu, Nurperi
dc.institutionauthoridOzan Başkurt / 0000-0003-1021-6529
dc.institutionauthoridNurperi Gazioğlu / 0000-0001-7785-8628
dc.language.isoen
dc.publisherMary ann liebert
dc.relation.ispartofSurgical infections
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAllergic Rhinitis
dc.subjectComplication
dc.subjectPituitary Abscess
dc.subjectPituitary Adenoma
dc.subjectSecondary Pituitary Abscess
dc.subjectTranssphenoidal Surgery
dc.titleSecondary pituitary abscess: a rare complication of transsphenoidal surgery for pituitary adenoma - description of two new cases and review of the literature
dc.typeOther

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