a new alternative approach to management of acute phase peyronie’s disease: low intensity extracorporeal shockwave therapy and platelet-rich plasma

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dc.authorscopusidAyhan Karaköse / 35769525800
dc.authorscopusidYasin Yitgin / 56562977600
dc.authorwosidAyhan Karaköse / CXJ-8166-2022
dc.authorwosidYasin Yitgin / ABE-9487-2020
dc.contributor.authorKaraköse, Ayhan
dc.contributor.authorYitgin, Yasin
dc.date.accessioned2025-04-18T08:31:59Z
dc.date.available2025-04-18T08:31:59Z
dc.date.issued2024
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü
dc.description.abstractBACKGROUND: The aim of this study was to investigate the efficacy, safety, and outcomes of the combination of low ıntensity external shock wave therapy (Li-ESWT) and platelet-rich plasma (PRP) therapy in acute phase Peyronie’s disease (PD). METHODS: The datas of patients admitted with acute phase Peyronie’s between January 2014 and January 2022 were reviewed retrospectively. In total, we included total 159 patients who used combination of vitamin E 600 mg/day plus colchicine 1.5 mg/day plus oral daily 5 mg tadalafil (N.=77) in group 1 and received Li-ESWT+PRP combination therapy plus oral daily 5 mg tadalafil (N.=82) in group 2. We noted characteristics of fibrous plaques, pain status, penile curvature degree, and erectile function parameters. all patients were visited at the 3rd and 12th months after the treatment. RESULTS: Preoperative demographic characteristics were similar in the two groups. There was a statistically significant improvement in the mean plaque size, penile curvature degree, IIEF-5 and VAS scores in the intervention group after the treatment. Ecchymosis and hematoma were not observed at the injection site and Li-ESWT application areas in the intervention group. No local or systemic drug reactions were noted in either group. CONCLUSIONS: Combination of Li-ESWT and PRP are highly effective and safety to early treatment in the acute phase pd. © 2023 EDIZIONI MINERVA MEDICA.
dc.identifier.citationKarakose, A., & Yitgin, Y. (2023). A new alternative approach to management of acute phase Peyronie's disease: low intensity extracorporeal shockwave therapy and platelet-rich plasma. Minerva Urology and Nephrology.
dc.identifier.doi10.23736/S2724-6051.23.05458-7
dc.identifier.endpage372
dc.identifier.issn27246051
dc.identifier.issue3
dc.identifier.pmid38093617
dc.identifier.scopus2-s2.0-85186582724
dc.identifier.scopusqualityQ1
dc.identifier.startpage367
dc.identifier.urihttp://dx.doi.org/10.23736/S2724-6051.23.05458-7
dc.identifier.urihttps://hdl.handle.net/20.500.12713/6578
dc.identifier.volume76
dc.identifier.wosWOS:001145843200001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorKaraköse, Ayhan
dc.institutionauthorYitgin, Yasin
dc.institutionauthoridAyhan Karaköse / 0000-0003-3905-1772
dc.institutionauthoridYasin Yitgin / 0000-0003-1111-6941
dc.language.isoen
dc.publisherEdizioni Minerva Medica
dc.relation.ispartofMinerva Urology and Nephrology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectPenile İnduration
dc.subjectPlatelet-rich Plasma
dc.subjectVisual Analog Scale
dc.titlea new alternative approach to management of acute phase peyronie’s disease: low intensity extracorporeal shockwave therapy and platelet-rich plasma
dc.typeArticle

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