Functionalized liposomes and niosomes for cancer therapy

Küçük Resim Yok

Tarih

2024

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Elsevier

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Liposomes and niosomes are two members of lipid-based nanocarriers superfamily that have attracted lots of attention in the cancer therapy subject due to their interesting structural features. They are vesicular nanoparticles composed of cholesterol and phospholipid (liposomes) or surfactant (niosomes) that have the most similarity with cellular membranes and have the capability of loading both hydrophobic and hydrophilic therapeutic agents. Moreover, the surface of these carriers could be functionalized with different compounds to enhance their stability, bioavailability, and targeting ability, which finally could lead to improved therapeutic performance. This book chapter aims to discuss functionalized liposomal and niosomal therapeutic nanoparticles for cancer treatment. To this end, we will first describe different structural features of liposomes and niosomes and their different preparation methods. Then we will mention different generations of liposomes and niosomes as well as different types of functionalization that could affect the stability, loading capacity, and bioavailability of these carriers in targeted cancer tissue. © 2024 Elsevier Inc. All rights reserved.

Açıklama

Anahtar Kelimeler

Cancer Therapy, Functional Nanomaterial, Liposome, Niosome, Targeting

Kaynak

Functionalized Nanomaterials for Cancer Research: Applications in Treatments, Tools and Devices

WoS Q Değeri

Scopus Q Değeri

N/A

Cilt

Sayı

Künye

Yavari, M., Foroushani, E. S., Nasri, N., Zarepour, A., Zarrabi, A., & Mostafavi, E. (2024). Functionalized liposomes and niosomes for cancer therapy. In Functionalized Nanomaterials for Cancer Research (pp. 345-363). Academic Press.