Follicular lymphoma: frequency and timing of treatment: single center experience

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dc.authorscopusidMehmet Hilmi Doğu / 55212747300
dc.authorwosidMehmet Hilmi Doğu / W-2255-2017
dc.contributor.authorKarışmaz, Abdulkadir
dc.contributor.authorCan Cavdar, Vahit
dc.contributor.authorSerin, İstemi
dc.contributor.authorDoğu, Mehmet Hilmi
dc.contributor.authorAslan, Ceyda
dc.contributor.authorEren, Rafet
dc.date.accessioned2025-04-17T07:21:25Z
dc.date.available2025-04-17T07:21:25Z
dc.date.issued2025
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractIntroduction: This study aimed to investigate how often follicular lymphoma (FL) occurs in patients diagnosed with non-Hodgkin lymphoma (NHL). Additionally, we investigated whether patients with FL required treatment, and if so, whether the need for treatment arose at the initial diagnosis or during subsequent follow-up periods. Methods: Six thousand five hundred sixty patients diagnosed with NHL or chronic lymphocytic leukemia were reached, and healthy data were obtained from 1,719 of them. Data from 176 patients diagnosed with FL were evaluated. Demographic information (age, gender) of the patients was collected. The classifications were grouped by taking into account World Health Organization data, the histological subtype of the tumor, gender and need for treatment were evaluated. Results: Among the patients, 55.1% (n=97) were men and 44.9% (n=79) were women. The median age of those with FL was 50 years, with ages ranging from 18 to 87. When looking at histological subtypes, the FL accounts for 10.2% of cases (n=176). The proportion of patients requiring treatment was 70.9% (125), and the proportion of patients followed up without treatment was 27.8% (49). Of the patients who needed treatment, 57.1% (n=101) required it at the time of diagnosis and 13.6% (n=24) during follow-up. Conclusion: FL, making up around 20% of all NHL, is the second most prevalent type of lymphoma in adults. The incidence, as well as the gender and age distribution, of FL can differ across populations. This may be related to ethnicity, geographical conditions, and socioeconomic status. In addition, the proportion of patients requiring treatment may also vary. When all these are taken into account, social differences are some of the main determinants in the approach to FL.
dc.identifier.citationKarışmaz, A., Çavdar, V. C., Serin, İ., Doğu, M. H., Aslan, C., & Eren, R. (2025). Follicular Lymphoma: Frequency and Timing of Treatment: Single Center Experience.
dc.identifier.doi10.4274/imj.galenos.2025.20788
dc.identifier.endpage67
dc.identifier.issn2619-9793
dc.identifier.issn2148-094X
dc.identifier.issue1
dc.identifier.startpage64
dc.identifier.urihttp://dx.doi.org/10.4274/imj.galenos.2025.20788
dc.identifier.urihttps://hdl.handle.net/20.500.12713/6118
dc.identifier.volume26
dc.identifier.wosWOS:001433864400001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.institutionauthorDoğu, Mehmet Hilmi
dc.institutionauthoridMehmet Hilmi Doğu / 0000-0001-7237-2637
dc.language.isoen
dc.publisherGalenos publishing house
dc.relation.ispartofIstanbul medical journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectFollicular
dc.subjectLymphomafrequency
dc.subjectTreatment Demand
dc.titleFollicular lymphoma: frequency and timing of treatment: single center experience
dc.typeArticle

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