Current Induction Therapy Strategies and Anti-T Lymphocyte Globulin Usage in Kidney Transplantation: Consensus-Based Recommendations by a Turkish Expert Panel
Küçük Resim Yok
Tarih
04.10.2024
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
AVES Yayıncılık
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
This advisory committee convened to review national and global kidney transplantation dynamics and provide recom- mendations on the use of anti-T lymphocyte globulin (ATLG) for prevention and treatment of rejection after allogeneic kidney transplantation. A critical evaluation of 6 relevant articles released up to October 2022 was performed to reveal their importance in clinical practice. Additionally, 27 key questions on the indication, dosage of ATLG, and risk stratification were used for the Delphi technique with 8 members of the Turkish Society of Nephrology including 5 kidney transplanta- tion (KTx) subcommittee members and a surgeon experienced in solid organ transplantation. The committee declared that Türkiye had great potential in KTx; however, increase in transplantation would be possible in the case of raise in the deceased donor transplantation. As a consensus, ATLG was strongly recommended for induction and rejection treatment. Also, committee members recommended the safe dosage range in steroid resistant acute rejection as 2.5-3 mg/kg daily for 5-7 days, and the median of preferred dosage in induction sounded as 2-2.5 mg/kg daily for 3 days in intermediate risk state. Additionally, post-transplant infection and malignancy cases due to immunosuppression were much rarely encoun- tered than they were in the past.
Açıklama
Anahtar Kelimeler
Anti-T-lymphocyte globulin, induction therapy, renal transplantation
Kaynak
Turkish journal of nephrology (Online)
WoS Q Değeri
Scopus Q Değeri
Cilt
33
Sayı
2
Künye
CAKIR, U., DINCKAN, A., KARADOĞAN, N., KEVEN, K., KOÇAK, H., KOÇ, S. K., SEZER, S., TÖZ, H., TURKMEN, A., TURKMEN, A., USALAN, C., YILDIZ, A., YILDIZ, A. (2024). Current Induction Therapy Strategies and Anti-T Lymphocyte Globulin Usage in Kidney Transplantation: Consensus-Based Recommendations by a Turkish Expert Panel. Turkish journal of nephrology (Online) , 33(2), 145 - 152. doi.org/10.5152/turkjnephrol.2024.23684
