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Öğe Effect of neurophysiological facilitation techniques on functional levels and respiratory in intensive care patients(EUROPEAN RESPIRATORY SOC JOURNALS LTD, 2021) Uyaroğlu, Mehmet Burak; Buran Çırak, Yasemin; Elbaşı, Nurgül Dürüstkan; Parlak, Hakan[No Abstract Available]Öğe A Life-threatening Adverse Effect of Taurinecontaining Energy Drink: Thrombocytopenia(Galenos Publ House, 2024) Ozyurt, Erhan; Parlak, Hakan; Inanoglu, Kerem; Ozturk, Nilgun Kavrut; Ozmen, SadikDue to the significantly increased consumption of energy drinks worldwide, reports of toxicity and adverse events related to these beverages are emerging in the literature. We report a 40 -year -old male patient who consumed eight to ten cans (2000 to 2500 mL) of taurine-containing energy drinks per day during the two weeks prior to hospitalization. The patient applied at the hospital with loss of consciousness and in the physical examination, petechia is detected in whole body. Laboratory values except platelet count were normal. We applied the plasmapheresis with a platelet count of 1300 mm3. On the fourth day, we extubated the patient whose clinical findings improved. On the sixth day, we measured the platelet count was 136,000 mm3, and transferred the patient to the hematology service. In conclusion, clinicians need to be aware of any potential side effects from using energy drinks.Öğe Paired exchange living donor liver transplantation: a single center experience from Turkiye(Elsevier inc., 2025) Dinçkan, Ayhan; Eren, Eryiğit; Ensaroğlu, Fatih; Şahin, Taylan; Parlak, Hakan; Koçyiğit, Ali; Alkara, Utku; Akyıldız, Murat; Tokaç, MehmetBackground. In countries with low rates of deceased donor solid organ transplantations, live- donor liver transplantation is the preferred definitive treatment for children and adults with end- stage liver disease. However, it is known that a remarkable number of potential living liver donors are rejected due to ABO incompatibility, suboptimal liver mass, or anatomical features. Paired exchange liver transplantation (PELT) practice emerged to overcome these obstacles. Herein, we present the results of our single-center experience with PELT and compare them with previously reported data. Methods. Patients who underwent PELT between January 2015 and December 2022 constituted the target population. The collected recipient data included demographic parameters, the model for end-stage liver disease score, graft-recipient weight ratio, indication for LT and paired exchange, body-mass index, duration of hospital stay, duration of intensive care unit stay, postoperative complications and inpatient mortality. Donor data, including demographic characteristics, body mass index, type of liver graft (right lobe or left lateral segment), graft weight (g), type of portal vein anatomy (Type 1, 2, or 3), type of biliary anatomy (Type 1, 2, 3a, 3b), duration of hospital stay, complications and mortality were retrieved. Results. Among 18 recipients, 14(78%) were male, and 4 (22%) were female. The mean recipient age was 50.7 [2-66], while the mean donor age was 29.3 [18-40]. The mean follow-up period was 31.9 [12-71] months. The 1-year patient and graft survivals were calculated as 83.3% and 88.9%. Conclusion. The PELT can be utterly feasible at transplant centers with remarkable LDLT experience.Öğe Results of using the cystic duct for reconstruction of one of the multiple bile ducts in right lobe living donor liver transplantation(Elsevier Inc., 2021) Özçelik, Ümit; Eren, Eryiğit; Tokaç, Mehmet; Şahin, Taylan; Parlak, Hakan; Dinçkan, AyhanAbstract Background: In right-lobe liver grafts, variations in the biliary tree anatomy can result in multiple bile duct orifices. We present our experience of 10 patients in which biliary reconstruction was performed with the cystic duct for 1 of the anastomoses with 2 separated ducts. Also, we investigated whether the bile duct anastomosis technique, number of bile duct anastomoses, and use of biliary stents affect the rate of biliary complications. Methods: We evaluated patients who underwent right-lobe living donor liver transplantation (LDLT) at İstinye University Hospital and İstanbul Aydın University Hospital between December 2017 and June 2020. The patients were divided into 4 groups: duct-to-duct (D-D), duct-to-sheath, double duct-to-duct, and duct-to-duct plus cystic duct-to-duct. Biliary complication rates were compared among these 4 groups, between single- and double-duct groups, and between stent (+) and stent (?) groups. Results: Ninety-three patients who underwent right-lobe LDLT (60 men, 33 women) with a mean age of 51 ± 13 years were included. Mean follow-up time was 18.5 ± 8.3 months. The overall biliary complication rate was 17.2% for all patients, 12.1% for the D-D (single-duct) group (33 patients), 16.1% for the duct-to-sheath group (31 patients), 26.3% for the double duct-to-duct group (19 patients), 20% for the duct-to-duct plus cystic duct-to-duct group (10 patients), 20% for the double-duct group (60 patients), 14.5% for the stent (+) group (69 patients), and 25% for the stent (?) group (24 patients). There were no significant differences among these groups in terms of biliary complication rates. Bile stricture occurred in only 1 cystic duct anastomosis (10%), and no bile leakage was observed. Conclusions: Multiple D-D biliary reconstruction using the cystic duct with external drainage tubes is feasible and safe for LDLT.