Yazar "Mergen, Azize" seçeneğine göre listele

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    Comparison of allogeneic stem cell transplantation results from related or unrelated donors in beta-thalassemia major
    (Nature Publishing Group, 2019) Aydoğdu, Selime; Mergen, Azize; Adaklı Aksoy, Başak; Çokluk, Mila N.; Dikme, Gürcan; Erol Cipe, Funda; Fışgın, Tunç; Bozkurt, Ceyhun
    Although there have been significant improvements with conventional therapies in beta thalassemia major, hematopoietic stem cell transplantation is only curative therapy. Related donors are preferred to diminish transplant risks. In lack of identical related donor, identical unrelated donors are second best choice. In this study, thalassemia major patients transplanted from unrelated donors (MUD) were compared with thalassemic patients transplanted from relative donor (MRD) retrospectively.
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    Comparison of turkish stem cell coordination center (TURKOK) with Istanbul university bone marrow bank (TRIS); A single center experience in match unrelated donors
    (Nature Publishing Group, 2019) Mergen, Azize; Aydoğdu, Selime; Adaklı Aksoy, Başak; Savcı, Yunus Emre; Dikme, Gürcan; Erol Cipe, Funda; Bozkurt, Ceyhun; Fışgın, Tunç
    Match family donors are the preferable options in allogenic stem cell transplant. However, in the absence of donor relatives match unrelated donors have been an option. In this study, the donor screening, transplant preparation phases of Turkish Stem Cell Coordination Center (TURKOK) and the İstanbul University Bone Marrow Bank (TRIS), were compared.
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    Donor lymphocyte infusion administrations after allogeneic stem cell transplantations in pediatrics: a single center experience
    (Nature Publishing Group, 2019) Aydoğdu, Selime; Mergen, Azize; Adaklı Aksoy, Başak; Akbay, Hazal S.; Erol Cipe, Funda; Dikme, Gürcan; Fışgın, Tunç; Bozkurt, Ceyhun
    Loss of chimerism is one of the major problems after allogeneic stem cell transplantation(SCT). Donor- lymphocyte infusions(DLI) are used as a treatment after taper or stopping immunosuppression. In this study, DLI experience in 20 patients with loss of chimerism after SCT due to various benign and malign hematological diseases was presented.
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    Extracorporeal photopheresis treatment for steroid resistant graft versus host disease in pediatrics: single center experience
    (Nature Publishing Group, 2019) Aksoy, Başak Adaklı; Savcı, Yunus Emre; Mergen, Azize; Aydoğdu, Selime; Dikme, Gürcan; Bozkurt, Ceyhun; Fışgın, Tunç
    Background: Steroid resistant graft vs host disease (GVHD) is de?ned as unresolved or worsened symptomatology of GVHD at day 14 despite effective immunosuppression with steroid therapy. Second line immunosuppressive agents, extracorporeal photopheresis (ECP) and/or mesenchymal stem cell therapies are being tried as salvage therapy.
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    Hit three birds with one stone: successful stem cell transplantation from one family donor to three siblings
    (Nature Publishing Group, 2019) Aksoy, Başak Adaklı; Aydoğdu, Selime; Dikme, Gürcan; Mergen, Azize; Bozkurt, Ceyhun; Fışgın, Tunç
    Background: Thalassemia major is a single gene related hereditary hemoglobinopaty required life long regular transfusions with chelation therapies. Stem cell transplantation is the only curative treatment of the disease. Three sibling thalassemia patients 13,4 and 3 years old were succesfully transplanted from their only donor,fully matched seventeen years old sister at our center.