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    Epidemiological, clinical, and laboratory features of children with COVID-19 in Turkey
    (FRONTIERS MEDIA SA, 2021) Karbuz, Adem; Akkoç, Gülşen; Bedir Demirdağ, Tuğba; Yılmaz Çiftdoğan, Dilek; Özer, Arife; Çakır, Deniz; Sütçü, Murat; Hatipoğlu, Halil Uğur
    Objectives: The aim of this study is to identify the epidemiological, clinical, and laboratory features of coronavirus disease 2019 (COVID-19) in children. Methods: A retrospective study was conducted by pediatric infectious disease specialists from 32 different hospitals from all over Turkey by case record forms. Pediatric cases who were diagnosed as COVID-19 between March 16, 2020, and June 15, 2020 were included. Case characteristics including age, sex, dates of disease onset and diagnosis, family, and contact information were recorded. Clinical data, including the duration and severity of symptoms, were also collected. Laboratory parameters like biochemical tests and complete blood count, chest X-ray, and chest computed tomography (CT) were determined. Results: There were 1,156 confirmed pediatric COVID-19 cases. In total, male cases constituted 50.3% (n = 582) and females constituted 49.7% (n = 574). The median age of the confirmed cases was 10.75 years (4.5-14.6). Of the total cases, 90 were younger than 1 year of age (7.8%), 108 were 1-3 years of age (9.3%), 148 were 3-6 years of age (12.8%), 298 were 6-12 years of age (25.8%), 233 were 12-15 years of age (20.2%), and 268 cases were older than 15 years of age (23.2%). The most common symptom of the patients at the first visit was fever (50.4%) (n = 583) for a median of 2 days (IQR: 1-3 days). Fever was median at 38.4 degrees C (38.0-38.7 degrees C). The second most common symptom was cough (n = 543, 46.9%). The other common symptoms were sore throat (n = 143, 12.4%), myalgia (n = 141, 12.2%), dyspnea (n = 118, 10.2%), diarrhea (n = 112, 9.7%), stomachache (n = 71, 6.1%), and nasal discharge (n = 63, 5.4%). When patients were classified according to disease severity, 263 (22.7%) patients were asymptomatic, 668 (57.7%) patients had mild disease, 209 (18.1%) had moderate disease, and 16 (1.5%) cases had severe disease. One hundred and forty-nine (12.9%) cases had underlying diseases among the total cases; 56% of the patients who had severe disease had an underlying condition (p < 0.01). The need for hospitalization did not differ between patients who had an underlying condition and those who do not have (p = 0.38), but the need for intensive care was higher in patients who had an underlying condition (p < 0.01). Forty-seven (31.5%) of the cases having underlying conditions had asthma or lung disease (38 of them had asthma). Conclusions: To the best of our knowledge, this is one of the largest pediatric data about confirmed COVID-19 cases. Children from all ages appear to be susceptible to COVID-19, and there is a significant difference in symptomatology and laboratory findings by means of age distribution.
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    Investigation of the relationship between short sleep duration and body mass index, nutritional habits and daily screen time in children (6-12 years)
    (2020) Sünnetci Silistre, Eda; Ayaş, Büşra; Hatipoğlu, Halil Uğur
    Abstract:Aim: The aim of this study is to evaluate obesogenic lifestyle and nutritional habits in a single study including a large population of children. Materials and Methods: A cross-sectional study was conducted with children aged between 6-12 years from 5 primary schools (n = 1002) in Istanbul, Turkey between April–June 2019. A questionnaire was filled which included information about weight, height, sleep duration, daily screen time and eating habits. Results: It was observed that obese children had significantly shorter sleep duration compared to children in other body mass index (BMI) groups (p = 0.001). It was found that median age was higher in children who slept less than 9 hours compared to those who slept 9 hours or more (p = 0.001). We also found that the median daily screen time of children who slept less than 9 hours was higher than the rest (p = 0.024). Conclusion: There was a significant relationship between short sleep duration and overweight / obesity prevalence and increased daily screen time. Sleep duration can be a potentially modifiable risk factor in the prevention and treatment of childhood obesity.
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    SARS-CoV-2 seropositivity among pediatric health care personnel after the first peak of the pandemic: nationwide surveillance in Turkey
    (Elsevier, 2021) Oygar, Pembe Derin; Büyükcam, Ayşe; Şahbudak Bal, Zümrüt; Dalgıç, Nazan; Bozdemir, Şefika Elmas; Sütçü, Murat; Gül, Doruk; Hatipoğlu, Halil Uğur
    Background: Understanding SARS-CoV-2 seroprevalence among health care personnel is important to explore risk factors for transmission, develop elimination strategies and form a view on the necessity and frequency of surveillance in the future. Methods: We enrolled 4927 health care personnel working in pediatric units at 32 hospitals from 7 different regions of Turkey in a study to determine SARS Co-V-2 seroprevalence after the first peak of the COVID-19 pandemic. A point of care serologic lateral flow rapid test kit for immunoglobulin (Ig)M/IgG was used. Seroprevalence and its association with demographic characteristics and possible risk factors were analyzed. Results: SARS-CoV-2 seropositivity prevalence in health care personnel tested was 6.1%. Seropositivity was more common among those who did not universally wear protective masks (10.6% vs 6.1%). Having a COVID-19-positive co-worker increased the likelihood of infection. The least and the most experienced personnel were more likely to be infected. Most of the seropositive health care personnel (68.0%) did not suspect that they had previously had COVID-19. Conclusions: Health surveillance for health care personnel involving routine point-of-care nucleic acid testing and monitoring personal protective equipment adherence are suggested as important strategies to protect health care personnel from COVID-19 and reduce nosocomial SARS-CoV-2 transmission. © 2021 The Author(s)