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    Association of dipping pattern of blood pressure and atherosclerotic burden of coronary arteries in hypertensive patients
    (Russian Heart Failure Soc., 2022) Taşbulak, Ömer; Aktemur, Tuğba; Şahin, Ahmet Anıl; Demir, Ali Rıza; Güler, Arda; Topel, Çağdaş; Türkvatan, Aysel; Pusuroğlu, Hamdi; Ertürk, Mehmet
    Aim The aim of this study was to determine the association between the dipping pattern of BP and coronary artery disease in hypertensive patients.Material and methods A total of 356 hypertensive patients were included in the study. The results of ambulatory BP monitoring, echocardiography, and coronary computerised tomographic angiography were evaluated retrospectively. The patients were divided into two groups on the basis of their ambulatory BP monitoring: 1) patients with the dipping pattern of BP; 2) patients with the non-dipping pattern (NDP).Results Among the 356 patients, 145 were male (40.7?%). The smoking status was higher in patients with NDP (p=0.023). The statin usage in patients with the dipping pattern was higher in patients with NDP (p=0.027). There were no significant differences in the echocardiographic findings. 58.6?% of the patients without plaque formation had the dipping pattern of BP (p<0.05), however 84.4?% of patients with >50?% plaque formation had the NDP of BP (p<0.001).Conclusion The NDP of BP might be related to the increased atherosclerotic process in coronary arteries, and pa-tients with NDP might have an increased atherosclerotic burden for coronary arteries when compared with patients with a dipping pattern.
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    The effect of uric acid and albumin ratio in undergoing lower extremity endovascular interventions for peripheral arterial disease related contrast induced nephropathy
    (Elsevier inc., 2024) Demirci, Gökhan; Şahin, Ahmet Anıl; Altunova, Mehmet; Aktemur, Tuğba; Atmaca, Sezgin; Yalçın, Ahmet Arif
    Background: Among patients undergoing percutaneous vascular intervention, contrast- induced nephropathy (CIN) is associated with increased morbidity and mortality. Serum uric acid/albumin ratio (UAR) has emerged as a new marker associated with poor cardiovascular outcomes. We aimed to evaluate the relationship between UAR and CIN occurrence in patients treated for peripheral artery disease. Methods: Patients underwent percutaneous intervention due to peripheral artery disease were enrolled. The primary endpoint was development of contrast related nephropathy. Patients were divided into 2 groups according to the CIN occurrence. Results: A total of 663 patients were enrolled and mean age was 62 +/- 10 years. After the intervention, 45 patients had CIN and 618 patients did not have CIN. Logistic regression analysis was performed to define the parameters of CIN. Male gender, diabetes, UAR, contrast volume, presence of coronary artery disease, and C-reactive protein levels were found significant in univariate analysis. However, only UAR was found significant in multivariate analysis (odds ratio 95% confidence interval: 3.426 (1.059-11.079), (P 1 / 4 0.040)).Therefore, it is the only independent predictor for occurrence of CIN. Conclusions: UAR is a reliable scoring system, which predicts CIN in such patient group. This score is not only cost-effective also simple, which can be easily applied into the clinical practice.